Could you share how you do that? It didn’t work last time I tried it (using Nix on top of Guix).

Depends on the system you are using, but the principle is the same.

First, you need to set up your profiles in about:profiles. Then, you launch these profiles with firefox -P "<profile name>" in your terminal. Once that works, you can use anything that can launch programs via keybindings. It’s easier on window managers. For example, in my Hyprland config, I have the following lines:

bind = SUPER, Z, exec, $browser -P "default"
bind = SUPER SHIFT, Z, exec, $browser -P "lesser" 

SUPER+Z launches my hardened browser (no JS), SUPER+SHIFT+Z launches my vanilla browser (JS enabled, some options turned off). The $browser variable is set to GNU Icecat, a Firefox fork.

You can create separate profiles with different settings. That means you will have to use a different profile (a separate browser instance) for some websites. I personally launch each profile with keybindings.

Update 2 months later: this was it. I just didn’t know how to install it on Mint. Turns out there’s a Driver Manager that you can use. Thanks!

That is true. IIRC, Krita is the only one of the 3 that has native CMYK support.

In my experience, Inkscape can be used as a professional replacement for Illustrator. It has never crashed on me. There may be some limitations, but nothing super inconvenient or something there isn’t a workaround for.

GIMP, on the other hand, is a mixed bag. I believe Krita is a much better candidate to be used professionally than GIMP. GIMP has an objectively bad UI, has weird quirks for very simple tasks, and is prone to crashes. I use GIMP for simple image editing and Krita for more complex projects. GIMP 3.0 is their best chance to fix their reputation and I’m hopeful it will deliver.

If you don’t have time to try them yourself, follow creators who use them and check their workflow. I recommend Davies Media Design on YouTube for great videos on Inkscape especially.

Edit: No program is completely immune to crashes, it’s good practice to routinely save projects no matter how stable or unstable the program is.

I recently flashed Mint on a MacBook Air 2012, but WiFi is really unstable and slow. Probably a driver issue. I had worse luck with Debian and Fedora.

For DAW, you may also want to check out Zrythm and Ardour.